For every symptom you elicit (whether itβs the presenting complaint or not), you must ask a series of further, symptom-specific questions β this is called exploring the symptom. After this, you must also ask relevant system review questions to determine the presence/absence of any significant associated features (see systems review ).
For all symptoms also review the timeframe
Duration
Onset: sudden or gradual (if sudden, what were they doing at the time?)
Progression
Timing: intermittent or continuous (if intermittent, are there any triggers/associations?)
Pain
Exploring pain
Generalised symptoms
Tiredness
Clarify what they mean by tiredness
What?
Constant or episodic?
Onset?
Duration?
Ask about sleep
Hours
Quality
Snoring/apnoeic episodes
How it affects the patient
Associated symptoms
Anaemia symptoms: breathlessness on exertion, dizziness/headache
Hypothyroidism symptoms: constipation, weight gain, cold intolerance, menorrhagia
Depression symptoms: mood, early morning waking
Diabetes symptoms: polydipsia, polyuria
A patient presents to ED with chest pain and this trace. What would you do?
Interpretation management
Covered in OSCE Stations
Cerebral symptoms
Headache
Explore as pain
Meningism symptoms: rash, fever, neck stiffness, photophobia
Giant cell arteritis symptoms: visual problems, jaw claudication, scalp tenderness (e.g. when brushing hair)
Glaucoma symptoms: visual blurring, red eye, halos around lights
Associated neurological symptoms (see notes on systems review )
Headache Red Flags:
Intracranial bleed: thunderclap headache, recent trauma
Raised intracranial pressure: posture/Valsalva-related
SOL: immunosuppression, malignancy, focal neurology, onset >50 years
Meningitis : rash, fever, neck stiffness, photophobia
Giant cell arteritis: visual problems, jaw claudication, scalp tenderness
Glaucoma: visual blurring, red eye, halos
Weakness
Pattern of weakness
Characterise weakness (e.g. fatigable in myasthenia gravis )
Associated neurological symptoms (see systems review )
Fit/fall/syncope
Fit/fall/syncope (get corroboration!)
Before: warning, circumstance
During : duration, LOC, movements (floppy/stiff/jerking), incontinence/tongue biting, complexion
After : amnesia, muscle pain, confusion/sleepiness, injuries from fall
Background to attacks: previous episodes, frequency, impact on life
! Check if patient drives β there may be driving restrictions
Chest symptoms
SOB
Current vs. normal exercise tolerance (what makes them stop?)
Orthopnoea
Paroxysmal nocturnal dyspnoea
Diurnal/seasonal variation if chronic
Associated cardiorespiratory symptoms (see systems review )
Cough
Productive or non-productive
Triggers
Nocturnal
Associated cardiorespiratory symptoms (see systems review )
Sputum
How much, how often
Colour, consistency
Any blood
Haemoptysis
Volume and frequency
Fresh or altered blood
Nature of associated sputum if any? Mixed in?
Palpitations
Fast or slow
Regular or irregular (ask patient to tap out palpitation on table)
Any dizziness, LOC, nausea, sweating/clamminess, dyspnoea
Associated cardiorespiratory symptoms (see systems review )
Abdominal symptoms
Diarrhoea / constipation / vomiting
How much, how often, any at night
Colour, consistency and contents (mucus, blood if diarrhoea ; blood, bile if vomiting )
Weight loss, appetite/intake
Associated gastrointestinal symptoms (see systems review )
Dysphagia
Solids/liquids/both, which came first
Constant/intermittent, progressive/non-progressive
Odynophagia
Weight loss, food intake
Associated gastrointestinal and neurological symptoms (see systems review )
Dyspepsia / reflux
Dyspepsia / Reflux red flags – ALARMS:
A naemia
L oss of weight
A norexia
R ecent onset progressive symptoms
M elaena/haematemesis
S wallowing difficulty; also: >55 years old, >4 weeks/relapsing symptoms, persistent vomiting
Gynaecological symptoms
Vaginal discharge
Quantity
Colour (including blood), odour, itching
Associated gynaecological symptoms (see systems review )
Abnormal PV bleeding
Type: menorrhagia, intermenstrual, post-coital, post-menopausal
Quantity of loss: number of sanitary towels/tampons, passage of clots/flooding
Pain with blood loss
Anaemia symptoms: tiredness, breathlessness on exertion
Thyroid symptoms
Chance of pregnancy
Associated gynaecological symptoms (see systems review )
Secondary amenorrhoea (work down the body)
General: weight loss, stress, exercise, diet
Head: visual problems, headaches
Thyroid: heat intolerance, tremor, palpitations, diarrhoea
Torso: hirsutism, acne
Abdomen: possibility of pregnancy
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Orthopaedic and rheumatological symptoms
Back pain
Explore as pain
Early morning stiffness
Sciatica
Urinary incontinence/retention, faecal incontinence/constipation
Associated neurological symptoms of lower limbs (see systems review )
Back pain red flags:
Cauda equina: urinary incontinence/retention, faecal incontinence/constipation, bilateral leg pain, severe/progressive neurological deficit, decreased anal tone/saddle anaesthesia
Infection or cancer: age <20 or >55 years at onset, weight loss, fever/night sweats, recent infection, cancer history, injecting drugs, immunosuppression
Fracture: trauma, severe central spinal pain, structural spine deformity, spinal tenderness
Spondyloarthropathy: early morning stiffness, night pain, worse with rest
Joint pain / stiffness / swelling
Worse in morning?, how long for (>30 minutes suggests inflammatory cause)
Better with exercise (inflammatory) or worse after exercise (osteoarthritis)
Sleep disturbance
Loss of function
Associated rheumatological symptoms (see systems review )
Bone / tissue / joint injury
Explore as pain
Stiffness/swelling
Movement restriction/ability to weight-bear
Mechanical symptoms: locking, giving way
Neurological symptoms distally: weakness, numbness, paraesthesia
Psychiatric symptoms
You must assess RISK in every psychiatric history. See here for psychiatric history .
Depression
Biological : sleep, energy, appetite
Future (including risk): hopelessness, suicidal thoughts/plans for suicide
Others: history of mania/hypomania
Anxiety
Timing: onset and duration, episodic/constant, triggers, effect on life, frequency
Somatic symptoms: palpitations, breathlessness, chest tightness, sweating, dizziness
Associated psychological symptoms: depression screen, stress, worry, avoidance
Psychiatric differential questions: obsessions, compulsions, post-traumatic stress disorder symptoms (psychological trauma, flashbacks, nightmares, hyperarousal)
Organic differential questions: e.g. hyperthyroidism symptoms, ACS symptoms
Auditory hallucinations
Voice detail: male/female, familiar/unfamiliar, always same/different, when heard etc.
Real/pseudo: out/inside of head
2nd /3rd person: to you/about you, comments
What they say (including commands)
Risk to self/others
Associated psychiatric symptoms (see psychiatric history )
Delusions
Memory loss
This is one where you need to get a collateral history .
Short/long-term
Insight and concerns
Functional levels (washing, dressing etc.)
Perform a cognitive assessment (e.g. mini mental state examination)
Risk to self/others
Eating disorder
BMI: weight, height
Symptoms: avoidance of weight gain/need to lose weight, preoccupation with appearance, efforts to purge (vomiting, laxatives, exercise), any binge eating/fasting
Food diary: what they eat each day
Results: menstrual cycle disturbance, poor dental hygiene
Screen for depression (including risk to self), diabetes and thyroid problems
Paediatric symptoms
Most symptoms are explored as you normally would for adults but some are specific. See here for full paediatric history .
Diarrhoea and vomiting
As normal, but include hydration questions (wet nappies, fluid intake, drowsiness)
Soiling / enuresis
Primary or secondary
Full account of toilet training
School toilet behaviour
Protest behaviour: stressful/chaotic life
If soiling: faeces consistency (diarrhoea/constipation β use Bristol Stool Chart ) and any painful anal conditions
If enuresis: have they ever had a dry night?
If secondary: urinary/GI infection symptoms, spinal cord compression symptoms (see systems review )
Failure to thrive / weight loss
Ask to see growth chart
Input : detailed dietary history, feeding history, hunger
Use : energy, activity level
Output : wet nappies, stools
Others: chronic cough (CF ), recurrent infections (CF, primary ciliary dyskinesia, immunological ), sweating/breathless when feeding (cardiac ), behaviour, general health, happiness, parentsβ health
Associated gastrointestinal symptoms (see systems review )
Weight gain
As for failure to thrive: see growth chart; input, use and output questions
Hypothyroidism symptoms: growth impairment, delayed puberty, mental slowness, constipation, cold intolerance
Cushingβs syndrome symptoms: growth impairment, proximal weakness, central obesity
Syndromic features , e.g. Laurence-Moon (extra digits, intellectual impairment), Prader-Willi (poor muscle tone, distinct facial features, lack of eye co-ordination)
Walking / sitting delay
Speech delay
Ages of milestones (see examination notes on child developmental assessment )
Senses: vocals, hearing, vision
Communication: comprehension (follows commands, responds to voice), non-verbal communication (pointing, gestures, facies), social responses (how acts in new situations, tantrums, playing, gestures)
Early puberty / late puberty / primary amenorrhoea / short stature
Pubertal development review: testes, breast development, menarche, pubic/axillary hair, height, acne, mood changes
Intracranial pressure symptoms: visual problems, headaches
Family pubertal/stature history
Symptoms of other systemic diseases (CF, thyroid disorder, anorexia, Crohnβs disease )
Behavioural disorder
Attention deficit hyperactivity disorder symptoms: poor concentration, hyperactivity
Conduct disorder symptoms: hostile, aggressive, cruel
Autism symptoms: poor social interaction, reciprocal communication behaviour, restricted interests, repetitive behaviours, difficulties recognising/responding to emotions
Allergies
Pattern, frequency, duration, persistent/intermittent
Reaction: wheeze, rash, sneezing/itchy eyes, abdominal pain/diarrhoea, swelling of eyes/eye-lids/tongue
Specifically ask about anaphylaxis symptoms
Triggers/associations: pollen/season, chemicals, pets, latex, dust, foods (milk/eggs/wheat/peanuts/fish/shellfish)
Ask about atopy in child and family (asthma, eczema, hay fever) and about food allergies
Ensure you ask about home (heating, dampness, pets) and social (smokers in family, exposure to pollutants)
Other symptoms
Rash
Duration, progression, frequency
Sites, size and shape
Description: what does it look like? Any blisters or raised areas? What colour is it? Does it blanch?
Secondary features: itchy/painful, crusting
Exacerbating/relieving factors, e.g. heat, sunlight, cold, treatment, allergies
Associated rheumatological symptoms (see systems review )
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Why don’t you test your knowledge?
You are taking a history from a patient with an episode of loss of consciousness. How would you explore this symptom further?
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Which systems reviews are pertinent and why?
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What conditions would be included in the differential diagnosis?
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Chest pain
Lower back pain
Difficulty hearing
Here’s a hard one!
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DOPTA
before during after
how much, how often,
has this happend before-previouse episodes
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