Multiple sclerosis is a chronic inflammatory disorder characterised by plaques of demyelination in central nervous system that cause neurological symptoms and disability.
Any part of central nervous system can be affected but common deficits include:
Diagnosis requires demonstration of demyelinating lesions โdisseminated in time and spaceโ
A patient presents to ED with chest pain and this trace. What would you do?
Interpretation management
Management requires a multi-disciplinary approach (including neurologist, specialist nurse, physiotherapist, occupational therapist, GP, speech and language therapist)
Suitable for some patients depending on type of MS:
Reference: NICE โNG220 Multiple sclerosis in adults: managementโ 2022
What is oscillopsia?
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Does multiple sclerosis cause upper or lower motor neuron lesions? Why?
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What is Lhermitte’s sign?
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What are the clinical findings of a internuclear ophthalmoplegia due to a right medial longitudinal fasciculus lesion?
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A patient presents to ED with chest pain and this trace. What would you do?
Interpretation management