Nephrotoxic drugs
Drugs to avoid/dose-reduce in renal impairment
Always look them up in the BNF if there is any renal impairment:
- Nephrotoxic drugs (above)
- Hypoglycaemics
- Drugs which increase potassium (e.g. supplements, potassium-sparing diuretics, ACE inhibitors)
- Antibiotics (e.g. ciprofloxacin, nitrofurantoin, some penicillins, trimethoprim, clarithromycin, teicoplanin)
- Opioids/NSAIDs
- Statins
- Ī²-blockers
- Psychotropics (e.g. lithium, gabapentin, fluoxetine)
- Anticoagulants (direct oral anticoagulants, low molecular weight heparin)
- Many others (e.g. allopurinol, colchicine, digoxin, ranitidine)
Try some relevant OSCE prescribing stations
- COPD exacerbation prescribing
- Pre-operative prescribing
- Neutropenic sepsis prescribing
- End of life medication prescribing
- Asthma exacerbation prescribing
- Find more stations here!
