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A transient loss of consciousness caused by a temporary drop in blood flow to the brain, often due to a reflex of the involuntary nervous system.
Most common cause of syncope in adults.
Pathophysiology
Overreaction of the parasympathetic nervous system (vagus nerve) leading to bradycardia (slow heart rate) and vasodilationΒ (widening of the blood vessels).
Results inreduced cardiac outputΒ and transient cerebral hypoperfusion.
Triggers
Emotional distress: Fear, severe pain, distressing sights.
Transient loss of consciousness (often less than a minute).
Recovery is typically rapid but may be associated with transient confusion.
Investigations π§ͺ
Investigations
Clinical history: Most diagnostic. Collateral history can help determine possible underlying causes.
ECG: To rule out cardiac causes.
Orthostatic blood pressure measurements.
Tilt table test: Diagnostic in some cases.
Holter monitor (ambulatory ECG monitor): If episodic or suspicion of arrhythmia.
Management π₯Ό
Management
Educate about triggers and early warning signs.
Counterpressure manoeuvres: Leg crossing, handgrip, arm tensing.
Increased salt and fluid intake.
Avoid prolonged standing, especially in hot environments.
Gradual physical training.
Pharmacological:Beta-blockers, fludrocortisone, SSRIs β used in recurrent cases.
Complications
Generally benign but has the potential for injury due to falls.
Recurrent episodes are common.
Key Points
Inappropriate reflex of the parasympathetic nervous system can cause a temporary drop in blood flow to the brain, resulting in a transient loss of consciousness.
Common triggers include emotional distress and standingΒ for long periods.
Typically preceded by prodromal symptoms (light headedness, nausea, feeling warm)
References
Jeanmonod, R., Sahni, D. and Silberman, M. (2023). Vasovagal Episode. [online] PubMed. Available at: https://www.ncbi.nlm.nih.gov/books/NBK470277/.
National Institute for Health and Care Excellence (2010). Introduction | Transient loss of consciousness (βblackoutsβ) in over 16s | Guidance | NICE. [online] www.nice.org.uk. Available at: https://www.nice.org.uk/guidance/cg109/chapter/Introduction.