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Mumps

Background knowledge 🧠

Definition

  • Acute viral illness caused by the mumps virus (genus Rubulavirus).
  • Characterised by parotitis (swelling of the parotid glands).
  • Mumps is a notifiable diseaseΒ therefore new cases must be reported to local health authorities.

Epidemiology

  • Common worldwide, particularly in unvaccinated populations.
  • Peak incidence in late winter and spring.
  • Most common in children aged 5-15 years.
  • Outbreaks still occur in the UK, particularly in areas with low vaccination coverage.

Aetiology and Pathophysiology

  • Caused by the mumps virus.
  • Transmitted via respiratory dropletsΒ and direct contact.
  • Incubation period: 14-25 days.
  • Virus infects the upper respiratory tract and then disseminates.
  • Affects salivary glands, CNS, pancreas, and testes.

Types

  • Typical mumps with parotitis.
  • Atypical mumps without parotitis.

Clinical Features 🌑️

Symptoms

  • Fever.
  • Headache.
  • Malaise.
  • Anorexia.
  • Myalgia.
  • Parotitis (unilateral or bilateral).

Signs

  • Swelling and tenderness of the parotid glands.
  • Earache.
  • Swelling of the Stensen duct opening.
  • Meningeal signs if associated with meningitis.
  • Orchitis in post-pubertal males.

Investigations πŸ§ͺ

Tests

  • Clinical diagnosis primarily.
  • Serology: mumps-specific IgM antibodies.
  • PCR for mumps RNA from throat swab.
  • Amylase levels may be elevated due to parotitis.

Management πŸ₯Ό

Management

  • Supportive care (hydration, analgesics, antipyretics).
  • Isolation to prevent spread.
  • Monitor for complications.
  • Scrotal support and cold packs for orchitis.

Complications

  • Orchitis.
  • Oophoritis.
  • Meningitis.
  • Encephalitis.
  • Deafness (usually unilateral).
  • Pancreatitis.

Prognosis

  • Generally good with full recovery.
  • Complications can occur, particularly in adults.
  • Lifelong immunity after infection.

Key Points

  • Vaccination is key to prevention.
  • Recognise symptoms early for isolation.
  • Diagnosis is primarily clinical but is confirmed with serology testing for mumps-specific IgM antibodies.
  • Monitor for and manage complications.
  • Education on vaccination importance.

References

Public Health England (2010). Notifiable diseases and causative organisms: how to report. [online] GOV.UK. Available at: https://www.gov.uk/guidance/notifiable-diseases-and-causative-organisms-how-to-report.

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