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Influenza

Background knowledge 🧠

Definition

Influenza is a highly contagious respiratory illness caused by influenza A or BΒ viruses.

Epidemiology

  • Seasonal outbreaks during winter months.
  • Pandemics can occur with new viral strains (e.g., H1N1 in 2009).

Transmission

  • Respiratory droplets: coughing and sneezing.
  • Direct contact: contaminated surfaces.

Clinical Features πŸŒ‘️

Symptoms

  • Rapid onset.
  • Fever and chills.
  • Muscle aches and fatigue.
  • Cough (usually dry).
  • Sore throat.
  • Headache.
  • Rhinorrhoea (runny nose).

Signs

  • Coryza.
  • Dry cough.
  • Small volume lymphadenopathy.

Investigations πŸ§ͺ

Tests

  • Combined nose and throat swab: PCR for virus detection.
  • Chest X-ray: if viral pneumonia is suspected or severe disease (influenza can cause a pneumonitis).
  • Blood tests: leukopenia, elevated CRP.

Management πŸ₯Ό

Management

  • Supportive care: rest, hydration, antipyretics.
  • Antivirals: oseltamivir or zanamivir may reduce the duration of symptoms if started within 48 hours of symptom onset.
  • Antibiotics only if secondary bacterial infection is suspected.

Prevention

  • Annual vaccination, especially for high-risk groups (elderly, healthcare workers, chronic medical conditions).
  • Hand hygiene and respiratory etiquette (covering mouth/nose when coughing/sneezing).
  • Isolation of infected individuals.

Complications

  • Secondary bacterial pneumonia: commonly caused by Staphylococcus aureus or Streptococcus pneumoniae.
  • Myositis and rhabdomyolysis.
  • Encephalitis and neurological manifestations (rare).
  • Myocarditis and pericarditis.
  • Otitis media: especially in children.

Key Points

  • Influenza is a highly contagious respiratory illness caused by influenza A or BΒ viruses.
  • Often presents with general systemic features such as muscle aches, fever and malaise along with coryzalΒ symptoms.
  • Investigation is primarily through a combined nose and throat swab to detect virus.
  • Management is primarily supportive, alongside antivirals and antibiotics if appropriate.
  • Prevention is important to prevent severe infection in high risk individuals.

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