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Bleeding from Upper GI Tract

Background Knowledge 🧠

Definition

Haemorrhage originating proximal to the ligament of Treitz, typically presenting as haematemesis (vomiting blood) or melaena (black, tarry stools).

Common Causes

  • Peptic ulcer disease: Gastric or duodenal ulcers due to NSAIDs or H. pylori.

  • Variceal bleeding: Secondary to portal hypertension,Β often due to cirrhosis.

  • Gastritis or duodenitis.

  • Mallory-Weiss tear: Tear at the gastro-oesophageal junction.

  • Gastric erosions.

  • Gastric cancer.

  • Dieulafoy’s lesion: Abnormal large artery that erodes the stomach wall.

Investigations πŸ§ͺ

Initial Tests

  • History & Examination: Assess severity, possible aetiology, and signs of shock.

  • Lab tests: Full blood count, coagulation profile, renal function, liver function tests.

Diagnostic Tests

  • Oesophagogastroduodenoscopy (OGD): First-line, allows direct visualisation and potential therapeutic intervention.

  • CT Angiography: In cases where OGD can’t localise bleeding.

Management πŸ₯Ό

Surgical Approach

  • Resuscitation: IV fluids, blood transfusion, correct coagulopathy, and monitor vitals.

  • For peptic ulcer bleeding uncontrolled by endoscopy:

    • Oversew of bleeding ulcer.
    • Vagotomy and antrectomy for recurrent or large ulcers.

  • For variceal bleeding:

    • Band ligation or sclerotherapy during OGD.
    • Transjugular intrahepatic portosystemic shunt (TIPS) if recurrent.
    • Surgical portosystemic shunts or oesophageal transection in select cases.

  • Preoperative Localisation: Ideally via OGD, or CT angiography if required.

  • Approach: Laparoscopic or open based on patient stability, surgeon expertise, and suspected pathology.

Post-operative Management

  • Monitor vital signs and haemoglobin levels.

  • Ensure adequate pain relief.

  • Proton pump inhibitors for ulcer disease.

  • Early mobilisation to prevent thromboembolic events.

  • Consider prophylactic antibiotics depending on procedure performed.

Key Points

  • Resuscitation and stabilisation are paramount in upper GI bleed.

  • OGD is essential for diagnosis, and often for treatment, of upper GI bleeds.

  • Surgical intervention is reserved for cases uncontrolled by endoscopic means or for certain specific pathologies.

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A 21-year-old girl has been out drinking with her friends. She is escorted into hospital by the paramedics after vomiting fresh blood. This occurred after several vomits without blood in. She is normally fit and well.

Which of the following is the most likely cause?


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