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Arterial Ulcer

Background Knowledge ๐Ÿง 

Definition

Arterial ulcers, also known as ischaemic ulcers, are wounds that occur due to inadequate blood flow, typically in the lower extremities. They result from arterial insufficiency, where there’s a reduction in blood flow to the extremities, leading to tissue ischaemia and necrosis.

Aetiology

  • Commonly caused by atherosclerosis, leading to decreased blood flow.

  • Other causes include thromboangiitis obliterans, diabetes mellitus, and traumatic injuries to arteries.

Pathophysiology

  • Reduced arterial flow leads to tissue hypoxia and necrosis.

  • The lack of sufficient blood flow impairs wound healing processes.

Clinical Features ๐ŸŒก๏ธ

Appearance

  • Located on areas of the feet and legs where there’s the least amount of subcutaneous tissue, like toes, lateral malleolus, or shin.

  • Typically small, round, and well-defined with a “punched out” appearance.

  • The base of the ulcer is usually pale, with minimal to no granulation tissue, and may be covered with necrotic tissue.

Symptoms

  • Pain is a significant feature, often severe and exacerbated by leg elevation.

  • Patients may report intermittent claudication or rest pain.

Associated Findings

  • Signs of peripheral arterial disease like diminished or absent pulses, pallor on elevation of the limb, and dependent rubor.

  • Trophic changes such as hair loss, thin shiny skin, and atrophy of subcutaneous tissue.

Investigations ๐Ÿงช

Clinical Assessment

  • Thorough history focusing on risk factors like smoking, diabetes, and hyperlipidaemia.

  • Physical examination for signs of arterial insufficiency.

Investigations

  • Ankle-brachial index (ABI) measurement is essential for assessing arterial flow.

  • Doppler ultrasound and angiography can be used for detailed vascular assessment.

Management ๐Ÿฅผ

General Principles

  • Primary aim is to improve arterial blood flow.

  • Control of risk factors like smoking cessation, glycaemic control in diabetics, and management of hyperlipidaemia.

Wound Care

  • Local wound care includes debridement of necrotic tissue and appropriate dressing.

  • Pain management is crucial due to the painful nature of these ulcers.

Surgical Intervention

Revascularisation procedures, such as angioplasty or bypass grafting, may be necessary in severe cases.

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Regarding arterial ulceration of the peripheries:

Arterial ulcers are intensely painful.

This is the classic site for venous ulceration. Arterial ulcers are located over the pressure areas of the foot, heel and toes.

Reversing the ischaemia can lead to complete healing of the ulcer.


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