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Appendicitis

Background Knowledge ๐Ÿง 

Definition

An inflammation of the appendix, a small pouch attached to the beginning of the large intestine.

Aetiology

Most commonly due to obstruction of the appendix lumen by faecoliths (hardened stool).

Clinical Features ๐ŸŒก๏ธ

Symptoms

  • Initial peri-umbilical abdominal pain that later localises to the right iliac fossa.

  • Associated symptoms: Nausea, vomiting, loss of appetite, and fever.

Signs

  • Examine for:
    • Signs of peritonitis.
    • Guarding and rigidity, rebound tenderness.
    • McBurney’s point tenderness: Point one-third the distance from the anterior superior iliac spine to the umbilicus.
    • Rovsing’s sign: Palpation of the LIF causes pain in the RIF.

Differential Diagnoses

  • Gastroenteritis
  • Ectopic pregnancy (in females)
  • Meckel’s diverticulitis
  • Urinary tract infections
  • Nephrolithiasis

Investigations ๐Ÿงช

Investigations

  • Full Blood Count (FBC): Elevated white cell count with neutrophilia.

  • Ultrasound: To visualise the appendix and check for any abscess or mass.

    • Potentially more useful in women where alternative pathology is considered more likely

  • CT scan: Higher sensitivity and specificity than ultrasound, especially in adults.

  • Urinalysis: To rule out urinary tract infection or nephrolithiasis as differential diagnoses.

Management ๐Ÿฅผ

Management

  • Surgical removal (appendicectomy): Gold standard; can be open or laparoscopic (more common).

  • Antibiotics: Empirical treatment for bacterial infections. Used both pre-operatively to reduce inflammation and post-operatively.

  • Pain relief with paracetamol or other suitable analgesics.

Complications

  • Peritonitis: Inflammation of the inner lining of the abdominal wall due to rupture of the appendix.

  • Abscess formation: Pus-filled mass inside the appendix or abdomen.

  • Adhesion: Bands of scar-like tissue that form between abdominal tissues and organs, causing them to stick together.

  • Sepsis

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Regarding acute appendicitis:

Young people are at highest risk.

Prophylactic peri-operative antibiotics are indicated.

Inflammation of the mesenteric lymph nodes is an important differential diagnosis in children.


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