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Anxiety, phobias and OCD

Differential Diagnosis Schema 🧠

Anxiety Disorders

  • Generalized Anxiety Disorder (GAD): Excessive, uncontrollable worry about various aspects of daily life, lasting at least 6 months.
  • Panic Disorder: Recurrent unexpected panic attacks, along with worry about future attacks or their consequences.
  • Social Anxiety Disorder (Social Phobia): Marked fear of social situations where one might be scrutinized by others, leading to avoidance.
  • Agoraphobia: Anxiety about being in situations where escape might be difficult or help unavailable if panic-like symptoms occur.

Phobias

  • Specific Phobias: Intense, irrational fear of a specific object or situation, leading to avoidance behavior.
  • Social Phobia: Overlapping with Social Anxiety Disorder, marked fear of social situations.
  • Agoraphobia: Often associated with panic disorder, fear of being in situations where escape is difficult.

Obsessive-Compulsive Disorder (OCD)

  • Obsessions: Recurrent, persistent, and intrusive thoughts, urges, or images causing marked anxiety.
  • Compulsions: Repetitive behaviors or mental acts performed in response to an obsession, aimed at reducing distress or preventing a feared event.

Other Mental Health Disorders

  • Depression: Persistent low mood, anhedonia, and feelings of worthlessness or guilt, which can co-exist with anxiety.
  • Post-Traumatic Stress Disorder (PTSD): Anxiety symptoms following exposure to a traumatic event, including flashbacks and avoidance.
  • Acute Stress Disorder: Similar to PTSD, but occurs within 1 month of the traumatic event.
  • Adjustment Disorder: Emotional or behavioral symptoms in response to a stressor, not meeting criteria for another disorder.

Medical Conditions

  • Hyperthyroidism: Symptoms can include anxiety, tremors, palpitations, and weight loss.
  • Cardiac Arrhythmias: Palpitations and a sense of impending doom can mimic anxiety.
  • Asthma: Can lead to hyperventilation, which may be misinterpreted as anxiety.
  • Pheochromocytoma: A rare tumor that can cause paroxysmal episodes of anxiety-like symptoms.

Key Points in History πŸ₯Ό

Symptoms

  • Onset: Sudden onset may suggest a panic attack or acute stress disorder, while gradual onset may be more consistent with GAD or OCD.
  • Duration: Persistent symptoms over 6 months are necessary for GAD diagnosis.
  • Triggers: Specific triggers may point towards phobias or PTSD, while non-specific triggers could suggest GAD.
  • Associated Physical Symptoms: Such as palpitations, sweating, or dizziness, common in anxiety disorders.
  • Avoidance Behavior: Common in phobias and OCD, where the patient avoids triggers of anxiety.
  • Repetitive Behaviors: Suggestive of OCD if the patient engages in ritualistic actions to alleviate distress.
  • Sleep Disturbance: Often reported in GAD and PTSD.
  • Impact on Daily Life: Assess the degree to which anxiety or compulsive behaviors interfere with normal functioning.

Background

  • Past Medical History: Look for a history of psychiatric disorders, thyroid disease, or other relevant medical conditions.
  • Drug History: Assess for use of stimulants (e.g., caffeine, amphetamines), corticosteroids, or withdrawal from substances, all of which can exacerbate anxiety.
  • Family History: A positive family history of anxiety, depression, or OCD can increase the likelihood of these disorders.
  • Social History: Consider recent life stressors, alcohol or drug use, and social support systems, which can all impact anxiety levels.
  • Childhood History: Early life stress or trauma can predispose to anxiety disorders and PTSD.

Possible Investigations 🌑️

Blood Tests

  • Full Blood Count (FBC): To rule out anemia or infection that could exacerbate anxiety.
  • Thyroid Function Tests: To exclude hyperthyroidism.
  • Electrolytes: To identify imbalances that could contribute to symptoms.
  • Blood Glucose: To rule out hypoglycemia.
  • Toxicology Screen: If substance use is suspected.

Imaging

  • ECG: To rule out cardiac causes for palpitations and chest pain.
  • MRI/CT Brain: Consider if neurological symptoms are present, or to exclude organic causes of anxiety.

Psychiatric Assessment

  • Screening Tools: Use validated tools such as GAD-7 for generalized anxiety, PHQ-9 for depression, or the Yale-Brown Obsessive Compulsive Scale for OCD.
  • Mental State Examination (MSE): Assess the patient’s appearance, behavior, mood, thoughts, perceptions, cognition, and insight.

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