Multiple sclerosis is a chronic inflammatory disorder characterised by plaques of demyelination in central nervous system that cause neurological symptoms and disability.
Any part of central nervous system can be affected but common deficits include:
Diagnosis requires demonstration of demyelinating lesions βdisseminated in time and spaceβ
A patient presents to ED with chest pain and this trace. What would you do?
Interpretation management
Management requires a multi-disciplinary approach (including neurologist, specialist nurse, physiotherapist, occupational therapist, GP, speech and language therapist)
Suitable for some patients depending on type of MS:
Reference: NICE βNG220 Multiple sclerosis in adults: managementβ 2022
What is oscillopsia?
Visual disturbance in which there is a to-and-fro movement (oscillation) of the visual fields.
What are the clinical features of upper and lower motor neuron lesions?
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Does multiple sclerosis cause upper or lower motor neuron lesions? Why?
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What is Lhermitte’s sign?
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What are the clinical findings of a internuclear ophthalmoplegia due to a right medial longitudinal fasciculus lesion?
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