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Monitoring narrow therapeutic range drugs

Please note OSCEstop content is for educational purposes only and not intended to inform clinical practice. OSCEstop and authors take no responsibility for errors or the use of any information displayed. Drugs and doses are intended for non-pregnant adults, who are not breastfeeding, with normal renal and hepatic function.

The therapeutic range of drugs is a concentration range that is high enough to ensure they work but not so high that they cause adverse effects. Some drugs have a particularly narrow therapeutic range and need close monitoring because a small increase in concentration can result in serious toxicity. Always use your local hospital protocols for dosing and monitoring. The below table gives some example protocols.

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